Hey Ospray,
If you shoot in RAW try using the sharpen options in the ACR (Adobe Camera Raw) interface, the little twin triangle icon in the menu bank just below the histogram.
Once opened you'll see four sliders - Amount, Radius, Detail & Masking.
Increase the image size to 100% before applying any adjustments.
Ammount adjusts the edge definition
Radius adjusts the size of the edge
Detail controls the level of sharpening applied to fine details like textures
Masking helps to restrict the sharpening to the main details
Here's a really neat feature, by holding down the Alt key whilst moving the slider you get an overlay mask and can see exactly where the sharpening is being applied. You can set the ammount as you want and know what's beeing sharpened
When you've done all the sharpening you can apply some noise reduction (if needed) all in the same dialogue box.
Those Guys at Adobe are the "Mut's Nut's"
Hope this is of help
Nige Wade