For me it is really worth it for several reasons:
1. Bouyancy. I prefer the weight of glass. It makes it easier to make my rig stable.
2. Reflections - I rarely have problems with good coated glass, I have had lots with acrylic
3. Durability - Acrylic will scratch with the slightest contact - glass is much more durable. Yes, you can repair acrylic but often at the expense of your optics, and it takes a looong time to repair.
4. Water shedding - For over-unders glass sheds water way better than acrylic
I have had a lot of acrylic and glass over the years, and I believe it is worth the investment to just get a good glass dome. It is an investment that, if you take care of it, will last a long time.