Seems to me that the world is composed of two types of people: the sheep, those that place more importance in "following the crowd" and the goats, those that value "individuality, innovation and advancement".
Life as a goat is not always easy, sometimes lonely, and, occasionally, you find that there is big price to pay for not sticking with the crowd. But the upside is that you will often discover new and better ways of doing things. You'll find a way of doing something new that'll stamp your mark on history.
In the computer world, we have Windoze users (sheep) and Apple users (goats). Over the years, Apple users have had some nervous moments when it looked like their platform would disappear. They've sometimes had to do without some software and computer games. But they've benefited by a much more usable, efficient, reliable system that enabled them to do things that the sheep could not. Even today, Windoze still can not accurately render colours...
In the world of photography, the sheep always pick Nikon and Canon. Honest products but almost never innovative. Olympus, on the other hand, has always been a risk taker, pushing innovation and making radical decisions. Not all of their innovation worked out and, at times, their strategy has wobbled about. But look at the features that has come out of their innovation.
Most of the discussion in this thread has focused on the relative dimensions of the 4/3rds system, no doubt prompted by its very name. But, if you study the concept closely, the dimensions are one of the least significant break-throughs. Lens coverage (sharpness from edge to edge), open standards, lens data transmission and camera body size are much more important factors. Throw in the self-cleaning sensor, the ergonomic layout and the dual storage media and you've got a very viable system.
Maybe the 4/3rds system will not become mainstream. But, how relevant is that. Leave the mainstream to the sheep. As long as the buyer can keep the system functioning for a reasonable equipment life time, the innovations will justify the investment.
Regards
Peter