I have been using one of several iTTL systems with my D700 for more than a year and a half. I started with Hartenberger 250's and the Heinrichs Weikamp TTL converter and more recently added Ikelite 161's and Ikelite's converter. Of the two, I find the Ikelite i-TTL system simpler because the converter is powered by the strobes, themselves, not a separate battery. I am reaching the point where at least 50% of the first shots I take of a subject are technically good enough for use and additional shots are taken primarily to provide different angles or framing or behavior.
My most recent dive was with a friend shooting with a Canon 5DmkII and manual strobes. To get his exposures right he almost always had to shoot 2, 3, or even 4 shots.
Flash-only shots with manual flash can be relatively simple. Just take the guide number and divide it by the distance. But when you try to add flash to a subject that is already lit by ambient light, you must reduce the output of the flash to less, sometimes much less, than a guide number for flash only would suggest. And this is where a TTL strobe, whose output you can vary with flash compensation can make things much easier. No necessity to move the flash(s) closer or farther away or reach up and change the power setting on the strobe or strobes. Just push the flach comp button and turn a dial to increase or decrease the strength of the flash(s). Much faster and more predictable.
If decent TTL for the digital cameras were not available I would probably still be shooting film. I want to get usable images on as many of one-shot opportunities as I can, and for me, TTL increases the successful number very significantly. I am not willing to go back to the dark ages of pre-TTL flash.
Fred